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Table 2 ALP, AST, ALT and creatinine serum biochemistry profiles of normal, negative control, AF2240-i-, and rAF-IL12-treated colon cancer-challenged mice after 28-days of treatments

From: Cytotoxicity study of the interleukin-12-expressing recombinant Newcastle disease virus strain, rAF-IL12, towards CT26 colon cancer cells in vitro and in vivo

 

ALP (U/L)

AST (U/L)

ALT (U/L)

Creatinine (Umol/L)

Normal

188.70 ± 7.50

122.00 ± 1.70

294.30 ± 2.00

33.00 ± 1.20

Negative control

284.00 ± 1.20*

208.00 ± 4.60*

392.30 ± 1.50*

42.00 ± 0.60*

AF2240-i

249.00 ± 13.90*

156.00 ± 2.30**

339.00 ± 1.70**

39.30 ± 0.30*

rAF-IL12

209.30 ± 0.58

148.00 ± 1.70**

316.00 ± 7.50***

39.00 ± 1.60*

  1. Data are presented as mean ± S.E.M from six mice per group. Mean values with statistical difference at p ≤ 0.05 between groups are indicated with *
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Cancer Cell International

ISSN: 1475-2867

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