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Table 2 ALP, AST, ALT and creatinine serum biochemistry profiles of normal, negative control, AF2240-i-, and rAF-IL12-treated colon cancer-challenged mice after 28-days of treatments

From: Cytotoxicity study of the interleukin-12-expressing recombinant Newcastle disease virus strain, rAF-IL12, towards CT26 colon cancer cells in vitro and in vivo

  ALP (U/L) AST (U/L) ALT (U/L) Creatinine (Umol/L)
Normal 188.70 ± 7.50 122.00 ± 1.70 294.30 ± 2.00 33.00 ± 1.20
Negative control 284.00 ± 1.20* 208.00 ± 4.60* 392.30 ± 1.50* 42.00 ± 0.60*
AF2240-i 249.00 ± 13.90* 156.00 ± 2.30** 339.00 ± 1.70** 39.30 ± 0.30*
rAF-IL12 209.30 ± 0.58 148.00 ± 1.70** 316.00 ± 7.50*** 39.00 ± 1.60*
  1. Data are presented as mean ± S.E.M from six mice per group. Mean values with statistical difference at p ≤ 0.05 between groups are indicated with *