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Table 2 Multivariate analysis of prognostic factors by Cox proportional hazard model

From: A methylation‐based mRNA signature predicts survival in patients with gastric cancer

Variables GSE15459 TCGA-GC GSE84437
HR (95%CI) P value HR (95% CI) P value HR (95% CI) P value
Age 1.09 (0.71–1.68) 0.709 1.96 (1.09–3.51) 0.025 1.83 (1.38–2.43) < 0.001
Eight-MDEGs signature
 High-risk vs. low-risk 2.28 (1.47–3.53) < 0.001 1.84 (1.13–2.99) 0.015 1.43 (1.09–1.88) 0.011
Gender
 Male vs. female 1.07 (0.68–1.68) 0.779 1.25 (0.71–2.22) 0.449 1.31 (0.96–1.77) 0.085
TNM stage
 III + IV vs. I + II 5.99 (3.27–10.99) < 0.001 2.24 (1.29–3.91) 0.004