Fig. 2
From: The MRTF-A/miR-155/SOX1 pathway mediates gastric cancer migration and invasion
MRTF-A plays a positive role in the regulation of miR-155 expression in GC cells. miR-155 expression was decreased by the selective MRTF-A inhibitor CCG-1423. a, b CCG-1423 inhibited miR-155 expression in SGC-7901 and MGC-803 cells. a–c Cells were treated with 10 μM CCG-1423 for 24 h. RNAs were examined by RT-qPCR. c CCG-1423 inhibited miR-155 promoter activity in SGC-7901 cells. miR-155 expression was stimulated by Cytochalasin D. d, e Cytochalasin D stimulated miR-155 expression in SGC-7901 and MGC-803 cells. d–e Cells were treated with 10 μM Cytochalasin D for 24 h. RNAs were examined by RT-qPCR. c Cytochalasin D increased miR-155 promoter activity in SGC-7901 cells. Data are shown as the mean ± S.E.M, based on three to six independent experiments. **, p < 0.01