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Table 2 Correlations between circ_0000527 and clinical characteristics in RB patients

From: Circ_0000527 promotes the progression of retinoblastoma by regulating miR-646/LRP6 axis

Pathological indicators Number of patients circ_0000527 expression P value
High Low
All cases 25 14 11  
Age (years)
 ≥ 5 4 1 3 0.173
 < 5 21 13 8  
Gender
 Male 12 6 6 0.561
 Female 13 8 5  
Tumor enucleated location
 Right 13 8 5 0.561
 Left 12 6 6  
Differentiation
 Well and moderate 15 6 9 0.048*
 Poor 10 8 2  
T classification
 T1 + T2 15 7 8 0.250
 T3 + T4 10 7 3  
N classification
 N0 11 4 7 0.080
 N1 + N2 14 10 4  
cTNM stage
 I + II 6 1 5 0.026*
 III + IV 19 13 6  
Largest tumor base (mm)
 ≥ 15 9 7 2 0.100
 < 15 16 7 9  
  1. *P < 0.05