From: Circ_0000527 promotes the progression of retinoblastoma by regulating miR-646/LRP6 axis
Pathological indicators | Number of patients | circ_0000527 expression | P value | |
---|---|---|---|---|
High | Low | |||
All cases | 25 | 14 | 11 | Â |
Age (years) | ||||
 ≥ 5 | 4 | 1 | 3 | 0.173 |
 < 5 | 21 | 13 | 8 |  |
Gender | ||||
 Male | 12 | 6 | 6 | 0.561 |
 Female | 13 | 8 | 5 |  |
Tumor enucleated location | ||||
 Right | 13 | 8 | 5 | 0.561 |
 Left | 12 | 6 | 6 |  |
Differentiation | ||||
 Well and moderate | 15 | 6 | 9 | 0.048* |
 Poor | 10 | 8 | 2 |  |
T classification | ||||
 T1 + T2 | 15 | 7 | 8 | 0.250 |
 T3 + T4 | 10 | 7 | 3 |  |
N classification | ||||
 N0 | 11 | 4 | 7 | 0.080 |
 N1 + N2 | 14 | 10 | 4 |  |
cTNM stage | ||||
 I + II | 6 | 1 | 5 | 0.026* |
 III + IV | 19 | 13 | 6 |  |
Largest tumor base (mm) | ||||
 ≥ 15 | 9 | 7 | 2 | 0.100 |
 < 15 | 16 | 7 | 9 |  |