Fig. 1

Differentially expressed pRCC mRNAs and miRNAs. Volcano plot (a) and heatmap (b) illustrated the differentially expressed mRNAs between tumor tissues and adjacent tissues. The differentially expressed miRNAs were illustrated in the volcano plot (c) and heatmap (d). The green dots represented the downregulated genes; the red dots represented the significantly upregulated genes, and the black dots represented the genes without differential expression. FDR < 0.05, log₂ | FC | > 1 and P < 0.05