Skip to main content

Table 2 GO and KEGG pathway enrichment analysis of DEGs in the most significant module

From: Identifying the novel key genes in renal cell carcinoma by bioinformatics analysis and cell experiments

Term/Pathway ID

Description

Count in gene set

P-value

BP

 GO:0006813

Potassium ion transport

4

2.29E−04

 GO:0055082

Cellular chemical homeostasis

5

5.69E−04

 GO:0006732

Coenzyme metabolic process

4

7.29E−04

 GO:0019752

Carboxylic acid metabolic process

5

9.93E−04

 GO:0043436

Oxoacid metabolic process

5

1.02E−03

 GO:0019725

Cellular homeostasis

5

1.02E−03

 GO:0051186

Cofactor metabolic process

4

1.30E−03

 GO:0006082

Organic acid metabolic process

5

1.41E−03

 GO:0035383

Thioester metabolic process

3

1.44E−03

 GO:0006637

Acyl-CoA metabolic process

3

1.44E−03

CC

 GO:0005759

Mitochondrial matrix

4

1.83E−03

 GO:0016324

Apical plasma membrane

3

1.33E−02

 GO:0070062

Extracellular exosome

6

1.70E−02

 GO:1903561

Extracellular vesicle

6

1.74E−02

 GO:0043230

Extracellular organelle

6

1.74E−02

 GO:0044429

Mitochondrial part

4

1.94E−02

 GO:0045177

Apical part of cell

3

1.98E−02

 GO:0030315

T-tubule

2

2.63E−02

 GO:0014704

Intercalated disc

2

3.06E−02

 GO:0044291

Cell–cell contact zone

2

4.08E−02

MF

 GO:0022804

Active transmembrane transporter activity

3

2.22E−02

KEGG

 hsa00020

Citrate cycle (TCA cycle)

3

5.07E−04

 hsa01130

Biosynthesis of antibiotics

4

1.44E−03

 hsa01200

Carbon metabolism

3

7.02E−03

 hsa04964

Proximal tubule bicarbonate reclamation

2

2.65E−02

 hsa01100

Metabolic pathways

5

3.76E−02

 hsa00260

Glycine, serine and threonine metabolism

2

4.45E−02

 hsa00620

Pyruvate metabolism

2

4.56E−02

  1. BP, biological process; CC, cellular component; MF, molecular function