From: Cyclin H predicts the poor prognosis and promotes the proliferation of ovarian cancer
Clinicopathological characteristic | No. Cases | Cyclin H Expression | R | P | |||
---|---|---|---|---|---|---|---|
0 | 1 | 2 | 3 | ||||
Age (years) | |||||||
< Mean | 27 | 1 | 8 | 10 | 8 | − 0.012 | 0.925 |
≥ Mean | 33 | 3 | 6 | 16 | 8 | ||
FIGO stage, n (%) | |||||||
I | 15 | 3 | 5 | 6 | 1 | 0.389 | 0.002* |
II | 6 | 0 | 3 | 1 | 2 | ||
III | 31 | 1 | 5 | 16 | 9 | ||
IV | 8 | 0 | 1 | 3 | 4 | ||
Histologic subtype, n (%) | |||||||
Serous papillary adenocarcinoma | 42 | 2 | 9 | 17 | 14 | − 0.228 | 0.079 |
Endometrioid adenocarcinoma | 7 | 1 | 2 | 2 | 2 | ||
Clear cell carcinoma | 3 | 0 | 1 | 2 | 0 | ||
Mucinous carcinoma | 8 | 1 | 2 | 5 | 0 | ||
Histologic grade, n (%) | |||||||
G1 | 20 | 4 | 7 | 7 | 2 | 0.466 | 0.0017*** |
G2 | 16 | 0 | 3 | 11 | 2 | ||
G3 | 24 | 0 | 4 | 8 | 12 | ||
Residual tumor (cm), n (%) | |||||||
≤ 1 | 45 | 3 | 12 | 20 | 10 | 0.166 | 0.194 |
> 1 | 15 | 1 | 2 | 6 | 6 | ||
Chemotherapy, n (%) | |||||||
Platinum only | 1 | 0 | 1 | 0 | 0 | 0.146 | 0.263 |
Other/platinum | 40 | 2 | 7 | 20 | 11 | ||
None | 10 | 2 | 6 | 6 | 5 | ||
Malignant tumor cells in peritoneal fluid | |||||||
Present | 31 | 3 | 10 | 13 | 5 | 0.308 | 0.016* |
Absent or rare | 29 | 1 | 4 | 13 | 11 |