Fig. 5
From: Long noncoding RNA HOTAIR promotes breast cancer development by targeting ZEB1 via sponging miR-601
ZEB1 was a target of miR-601 in BC. a The binding sites between miR-601 and ZEB1 3′UTR were shown. b, c Dual-luciferase reporter assay was used to confirm the interaction between miR-601 and ZEB1 3′UTR. d, e ZEB1 expression was markedly upregulated in BC tissues and cells compared to adjacent normal tissues and MCF-10A cells, respectively. f, g Pearson correlation analysis was performed to analyze the correlation between ZEB1 and miR-601 or HOTAIR. h WB analysis was used to detect ZEB1 protein expression to assess the effect of miR-601 overexpression on ZEB1 expression. *P < 0.05