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Fig. 4 | Cancer Cell International

Fig. 4

From: RETRACTED ARTICLE: Long non-coding RNA SATB2-AS1 inhibits microRNA-155-3p to suppress breast cancer cell growth by promoting breast cancer metastasis suppressor 1-like

Fig. 4

Inhibited miR-155-3p restricts malignant phenotypes of BC cells. a Expression of SATB2-AS1, miR-155-3p and BRMS1L mRNA in BC cell lines was detected by RT-qPCR after miR-155-3p intervention; b protein expression of BRMS1L in and BC cell lines was determined by western blot analysis after miR-155-3p intervention; c proliferation of BC cells was determined by MTT assay after miR-155-3p intervention; d colony formation ability of BC cells was measured by colony formation assay after miR-155-3p intervention; e flow cytometry was used to evaluate the apoptosis of BC cells after miR-155-3p intervention; f Transwell assay was employed to measure the migration ability of BC cells after miR-155-3p intervention; g Transwell assay was employed to measure the invasion ability of BC cells after miR-155-3p intervention; h tumor volume of nude mice that had been injected with BC cells was measured after miR-155-3p intervention; i tumor weight of nude mice that had been injected with BC cells was measured after miR-155-3p intervention. The measurement data conforming to the normal distribution were expressed as mean ± standard deviation, one-way ANOVA was used for comparisons among multiple groups and Tukey’s post hoc test was used for pairwise comparisons after one-way ANOVA

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