Skip to main content
Fig. 7 | Cancer Cell International

Fig. 7

From: Linc00473 potentiates cholangiocarcinoma progression by modulation of DDX5 expression via miR-506 regulation

Fig. 7

Linc00473 up-regulation increased tumor growth. a, b CCLP1 cells transfected with pcDNA3.1-linc00473 or pcDNA3.1-NC were separately injected subcutaneously into nude mice. On the 21st day following the injection, the tumors were removed after euthanasia. The tumor volumes were calculated every 3 days and the tumor weights were measured after excision. The results confirmed that linc00473 overexpression increased both the tumor volumes and the tumor weights. c, d The expression of miR-506 and DDX5 mRNA was detected by qRT-PCR. e Western blot results indicated that DDX5 expression was significantly increased in pcDNA3.1-linc00473 group. The error bars indicate the mean ± SD, and each experiment was repeated at least three times. *p < 0.05, **p < 0.01

Back to article page