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Fig. 4 | Cancer Cell International

Fig. 4

From: Long non-coding RNA LINC01426 facilitates glioblastoma progression via sponging miR-345-3p and upregulation of VAMP8

Fig. 4

LINC01426 is the molecular sponge of miR345-3p in GBM cell lines. a The binding site of LINC01426 and miR345-3p was predicted by Targetscan bank. b qRT-PCR determine the expression of miR345-3p in GBM cell lines. c, d The miR345-3p expression level was negatively correlated withLINC01426 in HS683 and U251 (c) or SW1783 (d) stable cell lines. e, f RIP assays showed Ago2 antibody enrichment ofLINC01426 and miR345-3p in U251 (e) and SW1783 (f). g Luciferase reporter assays showed miR-345-3p mimics significantly repressed the LINC01426 wild type reporter viability. In bg, the data are represented as mean ± SD of three times

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