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Fig. 7 | Cancer Cell International

Fig. 7

From: circ_0084927 promotes cervical carcinogenesis by sponging miR-1179 that suppresses CDK2, a cell cycle-related gene

Fig. 7

miR-1179 impaired cervical cancer cell cycle progression and adhesion and enhanced the apoptosis by suppressing CDK2. a The cell cycle progression of transfected HeLa and C-33A cells was identified by flow cytometry assay. b Cell–matrix adhesion assay was used to determine the adhesion ability of transfected HeLa and C-33A cells. c The apoptosis of the transfected HeLa and C-33A cells was determined by Caspase 3 activation experiment. a–c CON: blank control; NC: negative control; Si: CDK2 siRNA; inhibitor: miR-1179 inhibitor. NC, CDK2 siRNA, miR-1179 inhibitor or CDK2 siRNA plus miR-1179 inhibitor were transfected into HeLa and C-33A cells. The data of the three experiments were arranged in the form of mean ± SD. *P < 0.05, **P < 0.01, compared with the CON group, and #P < 0.05, ##P < 0.01, compared with the Si group

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