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Table 1 “Intrinsic” subtypes of breast cancer

From: EO771, the first luminal B mammary cancer cell line from C57BL/6 mice

“Intrinsic” subtypes of breast cancer

Estrogen receptors (ER)

Progesterone receptors (PR)

Human epidermal growth factor receptor 2 (HER2)

Other major characteristics

Luminal A

ER + 

PR ± 

HER2−

 

Luminal B

ER + 

PR ± 

HER2 + 

 

Triple negative or basal-like

ER−

PR−

HER2−

 

Triple negative claudin low

ER−

PR−

HER2−

Claudin-3, claudin-4 and claudin-7 low

HER2 + 

ER−

PR−

HER2 +