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Fig. 6 | Cancer Cell International

Fig. 6

From: Circ_0000190 suppresses gastric cancer progression potentially via inhibiting miR-1252/PAK3 pathway

Fig. 6

MiR-1252/PAK3 regulated inhibitory effect by circ_0000190 on gastric cancer cell growth. BGC-823 and MGC-803 cells were transfected with empty vectors or vectors inserted with circ_0000190 alone, or in combination with miR-1252 mimics or miR-1252 mimics and vectors containing PAK3 cDNA. PAK3 expression was determined by immunofluorescence (a) (blue DAPI, green PAK3). Cell viability was examined by CCK-8 assay, **P < 0.01, ***P < 0.001, compared with NC; ##P < 0.01, compared with OE andOE + mimics + PAK3 (b), Apoptosis was assayed by flow cytometry (c) and Hoechst staining (d). The cell proliferation was determined by Edu (e) and colony formation assay (f)

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