Skip to main content
Fig. 2 | Cancer Cell International

Fig. 2

From: Overexpressed GATA3 enhances the sensitivity of colorectal cancer cells to oxaliplatin through regulating MiR-29b

Fig. 2

GATA3 improves Oxa chemotherapy sensitivity in CRC. a, b HT-29 and DLD1 cell viability in each group. c–f Apoptosis and apoptosis rate of HT-29 and DLD1 cells in each group. g-h GATA3 and Caspase3 + cleaved caspase3 protein levels in HT-29 and DLD1 cells. The Oxa concentration of HT-29 cells was set to 11 μmol/L; the Oxa concentration of DLD1 cells was set to 28 μmol/L. OE Over expression, Oxa Oxaliplatin, shRNA GATA3 shRNA. Significance of P values in a, d and h: vs. Blank, **p < 0.01; vs. Oxaliplatin, ##p < 0.01; vs. GATA3 control + Oxa, ^^p < 0.01. Significance of P values in b, f, h: vs. Blank, **p < 0.01; vs. Oxaliplatin, ##p < 0.01; vs. GATA3 scramble + Oxaliplatin, ^^p < 0.01

Back to article page