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Fig. 3 | Cancer Cell International

Fig. 3

From: Overexpressed GATA3 enhances the sensitivity of colorectal cancer cells to oxaliplatin through regulating MiR-29b

Fig. 3

MiR-29b improves CRC sensitivity to Oxa chemotherapy. a, b Viabilities of HT-29 and DLD1 cells in each group. c–f Apoptosis and apoptosis rate of HT-29 and DLD1 cells in each group. g–h Caspase3 + cleaved caspase3 protein levels in HT-29 and DLD1 cells. i–j MiR-29b mRNA levels in HT-29 and DLD1 cells. The Oxa concentration of HT-29 cells was set to 11 µmol/L; the Oxa concentration of DLD1 cells was set to 28µmol/L. Oxa Oxaliplatin, NC negative control, Agomir miR-29b agomir, Antigomir miR-29b antagomir. Significance of P values in a, d, h, i: vs. Blank, **p < 0.01; vs. Oxaliplatin, ##p < 0.01; vs. miR-29b agomir NC + Oxaliplatin, ^^p < 0.01. Significance of P values in b, f, h, i : vs. Blank, **p < 0.01; vs. Oxaliplatin, ##p < 0.01; vs. miR-29b antagomir NC + Oxaliplatin, ^^p < 0.01

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