Skip to main content
Fig. 8 | Cancer Cell International

Fig. 8

From: Long non-coding RNA KCNQ1OT1 up-regulates CTNND1 by sponging miR-329-3p to induce the proliferation, migration, invasion, and inhibit apoptosis of colorectal cancer cells

Fig. 8

KCNQ1OT1knockdown suppressed CRC tumor growth by regulating of miR-329-3p/CTNND1axis in vivo. a, b Tumor volume and tumor weight were measured in xenografts. c The expression levels of KCNQ1OT1,miR-329-3p and CTNND1 in xenografts were assessed by RT-qPCR. d CTNND1 protein level was detected in xenografts. The protein levels of CyclinD1, Bcl-2, and Cleaved-casp-3 were measured in xenografts. e The expression levels of CyclinD1, apoptosis-associated proteins (Bcl-2, Cleaved-casp-3) and the control (GAPDH) were evaluated by western blot in xenografts transfected with sh-KCNQ1OT1 or sh-control. *P < 0.05, vs. control group

Back to article page