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Fig. 1 | Cancer Cell International

Fig. 1

From: Identification of prognosis-related genes and construction of multi-regulatory networks in pancreatic cancer microenvironment by bioinformatics analysis

Fig. 1

Immune scores and stromal scores were associated with pathologic stages and overall survival of pancreatic patients. a Work flow of the present study. b Distribution of immune scores of different pathologic stages. Box‐plot showed significant association between pathologic stages and the level of immune scores (n = 177, p = 0.00798). c Distribution of stromal scores of different pathologic stages. Box‐plot showed no significant association between pathologic stages and the level of stromal scores (n = 177, p = 0.1172). d TCGA cohort samples were divided into two groups based on their immune scores: the 139 cases with immune scores higher than 0 and the 38 cases with immune scores lower than 0. As shown in the Kaplan‐Meier survival curves, median survival of the low score group was significantly longer than high score group (p = 0.024 in log-rank test). e Similarly, TCGA cohort samples were divided into two groups based on their stromal scores: the 135 cases with stromal scores higher than 0 and the 42 cases lower than 0. The median survival of the low score group was longer than the high score group, althougth not statistically different as indicated by the p = 0.37 in log-rank test

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