Fig. 2

Comparison of gene expression profile with immune scores and stromal scores in pancreatic cancer. Heatmaps were drawn based on the methods of average linkage and Pearson distance measurement. Genes with higher expression were shown in red while lower expression genes were in green. a Heatmap of the DEGs of immune scores higher than 0 vs. immune scores lower than 0 (p < 0.05, FC > 2). b Heatmap of the DEGs of stromal scores higher than 0 vs. stromal scores lower than 0 (p < 0.05, FC > 2). c, d Venn diagrams showing the number of commonly upregulated (c) or downregulated (d) DEGs in immune and stromal score groups. Top 10 terms of GO (e), KEGG pathway (f) and KEGG disease (g) were acquired from KOBAS 3.0 annotation and enrichment tool. p < 0.05