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Fig. 3 | Cancer Cell International

Fig. 3

From: Inhibition of Delta-like Ligand 4 enhances the radiosensitivity and inhibits migration in cervical cancer via the reversion of epithelial–mesenchymal transition

Fig. 3

Western blot analysis demonstrated that DLL4 downregulation inhibits the EMT in the irradiated CC cells and DLL4 is upregulated in the CC-RR group. a Western blot analysis of the migration- and EMT-associated protein expression levels in the DLL4-siRNA group and control groups in the irradiated Caski and SiHa cells, GAPDH was used as the normalization control. b E-cadherin and vimentin analysis by immunofluorescence was conducted to detect the function of DLL4 on the regulation of EMT. c The DLL4 protein level detected by Western blot analysis and d the DLL4 mRNA level detected by Real-time PCR in radioresistance CC (CC-RR) group was significantly upregulated compared with that in radiosensitivity CC (CC-RS) group. The data are presented as mean ± SD, **P < 0.01, ***P < 0.001

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