Fig. 5

RACK1 suppresses CCNO expression through enhancement of miR-302b-3p, miR-302c -3p or miR-302d-3p expression. a The expression of RACK1, miR-302b/c/d-3p, and CCNO in cells detected by RT-qPCR, *p < 0.05 vs. cells treated with oe-NC; b Protein levels of RACK1 and CCNO examined by Western blot analysis, with protein bands assessed, *p < 0.05 vs. cells treated with oe-NC; c The correlation between RACK1 and miR-302b/c/d-3p in CasKi cells analyzed by Pearson’s correlation coefficient; d Positive expression of RACK1 protein in CSCC (N = 46) and normal cervical tissues (N = 30) detected by immunohistochemistry (×400). *p < 0.05 vs. cells treated with oe-NC. The values in the figure were measurement data, and expressed as mean ± standard deviation. Independent sample t test was used for data comparison between two groups. The experiment was repeated 3 times independently