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Fig. 2 | Cancer Cell International

Fig. 2

From: CircRNA hsa_circRNA_0001776 inhibits proliferation and promotes apoptosis in endometrial cancer via downregulating LRIG2 by sponging miR-182

Fig. 2

Circ_0001776 overexpression suppressed proliferation and facilitated apoptosis of EC cells. a, b Circ_0001776 resistance to RNase R was detected by RT-qPCR. c, d RT-qPCR was used to assess the levels of cytoplasmic control transcript (GAPDH), nuclear control transcript (U6) and circ_0001776 in nuclear and cytoplasmic fractions. e, f The overexpression efficiency of circ_0001776 was evaluated by RT-qPCR. gi Cell proliferation in EC cells transfected with circ_0001776 or vector was detected by CCK-8 assay and colony formation assays. j Cell apoptosis in EC cells transfected with circ_0001776 or vector was measured by flow cytometry analysis. **P < 0.01

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