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Table 3 Identification of novel mutations in the patient tumor by using whole-exome sequencing

From: Characterization and comparison of genomic profiles between primary cancer cell lines and parent atypical meningioma tumors

Chromosome Gene Position Class Variants Biotype
chr3 SFMBT1 52966180 Predicted intracellular proteins c.598G > T Protein_coding
(p.Glu200*)
chr3 ETV5 185797800 cancer-related genes, predicted intracellular proteins, transcription factors c.456A > C Protein_coding
(p.Pro152Pro)
chr4 CORIN 47644083 Disease-related genes, enzymes, plasma proteins, potential drug targets, predicted intracellular proteins c.*832G > T,c.2069-17G > T,c.1757-17G > T Protein_coding
chr4 FSTL5 162697050 Predicted secreted proteins c.586G > A,c.583G > A,c.583G > A Protein_coding
(p.Asp196Asn,p.Asp195Asn,p.Asp195Asn)
chr6 SNRNP48 7609079 Predicted intracellular proteins c.993T > G Protein_coding
(p.Ser331Arg)
chr9 ADAMTSL2 136405721 Disease-related genes, plasma proteins, predicted intracellular proteins, predicted secreted proteins c.414T > A,c.414T > A Protein_coding
(p.Asp138Glu,p.Asp138Glu)
chr10 SFMBT2 7423901 Predicted intracellular proteins c.-41C > T,c.-41C > T,c.-41C > T,c.-41C > T Protein_coding
chr11 MRGPRX2 19077162 G-protein coupled receptors, predicted membrane proteins c.788T > C,c.788T > C Protein_coding
(p.Val263Ala,p.Val263Ala)
chr12 ARHGEF25 58006730 Predicted intracellular proteins c.232G > T,c.115G > T,n.698 + 51G > T Protein_coding
(p.Gly78Cys,p.Gly39Cys)
chr12 DTX3 58006730 Predicted intracellular proteins c.*3795G > T,c.*3795G > T,c.*3795G > T Protein_coding
chr12 SRRM4 119594473 Predicted intracellular proteins c.1706G > A Protein_coding
(p.Ser569Asn)
chr12 HCAR1 123214716 G-protein coupled receptors, predicted membrane proteins, transporters c.171G > A Protein_coding
(p.Leu57Leu)
chr15 RGMA 93595562 Predicted intracellular proteins, predicted secreted proteins c.330C > A,c.258C > A,c.258C > A,c.258C > A,c.258C > A,c.306C > A Protein_coding
(p.Ala110Ala,p.Ala86Ala,p.Ala86Ala,
p.Ala86Ala,p.Ala86Ala,p.Ala102Ala)
chr17 TMEM132E 32964719 Disease-related genes, predicted membrane proteins c.2693T > G Protein_coding
(p.Phe898Cys)
chr20 MYBL2 42328630 Cancer-related genes, predicted intracellular proteins, transcription factors c.897C > T,c.825C > T Protein_coding
(p.Leu299Leu,p.Leu275Leu)