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Table 3 The possible mechanisms of lncRNAs in ATC

From: Molecular mechanisms of long non-coding RNAs in anaplastic thyroid cancer: a systematic review

LncRNA Cell proliferation/viability/growth Cell cycle Invasion Cellular function
Migration Apoptosis Differentiation Autophagy CSC properties
LOC100507661      
GAS5       
H19     
UCA1      
HCP5       
KLHL14-AS      
Linc00210       
TNRC6C-AS1      
AK139328      
LINC00312      
XIST        
SNHG7       
SNHG15      
ZFAS1       
CASC2       
ROR        
PVT1      
HOTAIR        
MALAT1   
BANCR      
FOXD2-AS1        
PTCSC3     
MANCR     
PAR5       
TUG1     
  1. lncRNAs such as MIR22HG, HOTAIRM1, and PCA3 are involved in the development, progression, and prognosis of ATC, their function in different cellular processes have not yet been determined
  2. BANCR, BRAF-activated non-protein coding RNA; CASC2, cancer susceptibility candidate 2; CSC, cancer stem cell; FOXD2-AS1, FOXD2 adjacent opposite strand RNA 1; GAS5, growth arrest special 5; HCP5, HLA complex P5; HOTAIR, HOX transcript antisense RNA; Klhl14, kelch like family member 14; Linc00210, long intergenic non-protein coding RNA 210; LINC00312, long intergenic non-protein coding RNA 312; LncRNA, long noncoding RNA, MALAT1: metastasis-associated lung adenocarcinoma transcript 1; MANCR, mitotically associated long non coding RNA; PAR5, Prader Wili/Angelman region RNA 5; PTCSC3, papillary thyroid carcinoma susceptibility candidate 3; PVT1, plasmacytoma variant translocation 1; ROR, regulator of reprogramming; SNHG15, small nucleolar RNA host gene 15; SNHG7, small nucleolar RNA host gene 7; TNRC6C-AS1, TNRC6C antisense RNA 1; TUG1, taurine up-regulated gene 1; UCA1, urothelial carcinoma-associated 1; XIST, X inactive specific transcript; ZFAS1, ZNFX1 antisense RNA 1