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Fig. 3 | Cancer Cell International

Fig. 3

From: Circular RNA circ_0020123 promotes non-small cell lung cancer progression by sponging miR-590-5p to regulate THBS2

Fig. 3

Circ_0020123 directly targeted miR-590-5p. a The binding site between circ_0020123 and miR-590-5p was detected by the online software starBase 3.0. b The luciferase activity of circ_0020123-WT or circ_0020123-MUT reporter plasmid in A549 and H1299 cells transfected with miR-NC or miR-590-5p was detected by dual-luciferase reporter assay. c QRT-PCR was used to detect the expression of miR-590-5p in A549 and H1299 cells. d The expression of miR-590-5p in A549 and H1299 cells transfected with si-circ_0020123-1 or si-circ_0020123-2 was detected by qRT-PCR. e RIP assay was used to confirm the relationship between circ_0020123 and miR-590-5p. *P < 0.05

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Cancer Cell International

ISSN: 1475-2867

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