Fig. 4

MiR-590-5p downregulation reversed circ_0020123 knockdown effects in NSCLC cells. a QRT-PCR was used to detect the expression of miR-590-5p in A549 and H1299 cells transfected with miR-590-5p-inhibitors. b The expression of miR-590-5p in A549 and H1299 cells transfected with si-circ_0020123-1 or si-circ_0020123-1 + miR-590-5p-inhibitors was detected by qRT-PCR. c The proliferation of A549 and H1299 cells transfected with si-circ_0020123-1 or si-circ_0020123-1 + miR-590-5p-inhibitors was tested by CCK-8 assay. d Transwell assay was used to measure the migration of A549 and H1299 cells transfected with si-circ_0020123-1 or si-circ_0020123-1 + miR-590-5p-inhibitors. e Flow cytolysis assay was used to detect the apoptosis of A549 and H1299 cells transfected with si-circ_0020123-1 or si-circ_0020123-1 + miR-590-5p-inhibitors. f The protein levels of Ki-67, MMP-9, Cleaved-casp9 in A549 and H1299 cells transfected with si-circ_0020123-1 or si-circ_0020123-1 + miR-590-5p-inhibitors were detected by Western blot. *P < 0.05