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Fig. 2 | Cancer Cell International

Fig. 2

From: LncRNA DLX6-AS1 aggravates the development of ovarian cancer via modulating FHL2 by sponging miR-195-5p

Fig. 2

DLX6-AS1 knockdown inhibited OC cells proliferation, migration, and invasion but induced apoptosis. SKOV3 and A2780 cells were transfected with si-DLX6-AS1, with si-NC as a control. a The efficiency of DLX6-AS1 knockdown was checked by qRT-PCR in transfected cells. b Cell proliferation was assessed by CCK-8 assay in OC cells with DLX6-AS1 knockdown. c Cell apoptosis was monitored by flow cytometry assay in OC cells with DLX6-AS1 knockdown. d, e The protein levels of PCNA and C-caspase 3 in OC cells with DLX6-AS1 knockdown were quantified by western blot analysis. f, g Cell migration and invasion were detected by transwell assay in OC cells with DLX6-AS1 knockdown. h, i The protein levels of N-cadherin, Vimentin and E-cadherin in OC cells with DLX6-AS1 knockdown were quantified by western blot analysis. *P < 0.05

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Cancer Cell International

ISSN: 1475-2867

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