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Fig. 4 | Cancer Cell International

Fig. 4

From: LncRNA DLX6-AS1 aggravates the development of ovarian cancer via modulating FHL2 by sponging miR-195-5p

Fig. 4

MiR-195-5p inhibition reversed the effects of DLX6-AS1 knockdown on OC cells proliferation, apoptosis, migration and invasion. SKOV3 and A2780 cells were transfected with si-DLX6-AS1, si-NC, si-DLX6-AS1 + anti-miR-195-5p and si-DLX6-AS1 + anti-NC, respectively. a The expression level of miR-195-5p was measured by qRT-PCR in indicated cells. b Cell proliferation was assessed by CCK-8 assay in indicated cells. c, d Cell apoptosis was monitored by flow cytometry assay in indicated cells. e, f The protein levels of PCNA and C-caspase 3 in indicated cells were quantified by western blot analysis. g, h Cell migration and invasion were detected by transwell assay in indicated cells. i, j The protein levels of N-cadherin, Vimentin and E-cadherin in indicated cells were quantified by western blot analysis. *P < 0.05

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