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Fig. 6 | Cancer Cell International

Fig. 6

From: LncRNA DLX6-AS1 aggravates the development of ovarian cancer via modulating FHL2 by sponging miR-195-5p

Fig. 6

FHL2 overexpression reversed the influences of miR-195-5p enrichment on OC cells proliferation, apoptosis, migration and invasion. SKOV3 and A2780 cells were transfected with miR-195-5p, NC, miR-195-5p + FHL2 and miR-195-5p + vector, respectively. a The protein level of FHL2 in mentioned transfected cells was measured by western blot. b Cell proliferation was assessed by CCK-8 assay in mentioned transfected cells. c Cell apoptosis was monitored by flow cytometry assay in mentioned transfected cells. d, e The protein levels of PCNA and C-caspase 3 in mentioned transfected cells were quantified by western blot analysis. f, g Cell migration and invasion were detected by transwell assay in mentioned transfected cells. h, i The protein levels of N-cadherin, Vimentin and E-cadherin in mentioned transfected cells were quantified by western blot analysis. *P < 0.05

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