Fig. 4From: Evaluation of the upregulation and surface expression of hypoxanthine guanine phosphoribosyltransferase in acute lymphoblastic leukemia and Burkitt’s B cell lymphomaHPRT knockdown confirmation. Following knockdown of HPRT, a western blot was performed to both confirm knockdown status and to also quantify the internal cellular expression of HPRT within Raji cells and healthy PBMC. Knockdown cells had significantly decreased levels of HPRT in total cell lysate, indicating successful knockdown (p-value = 0.0002). Healthy PBMCs had significantly lower total HPRT than Raji samplesBack to article page