Fig. 5

Genomic Characterization of the organoids derived from a mammary Paget’s disease patient. a, b Scatterplot and circos plot illustrating genome copy number alterations of the organoids which showed clean copy number signals and changes in copy number gains or losses were not obvious. c Bar graph showing the relative contributions of point mutation types underlying mutational signatures for the organoids. d Somatic mutations found in breast cancer genes of the organoids