Fig. 1

Knockdown of LINC00152 decreases the proliferation and invasion of lung cancer cells in vitro. a LINC00152 expression was analyzed by qRT-PCR in 5 NSCLC cell lines that were compared with the normal human bronchial epithelial cell line (16HBE). b, c LINC00152 mRNA levels in SPCA1 (b) and A549 (c) with LINC00152 siRNA (si-LINC00152) transfection compared with the negative control siRNA (NC) by qRT-PCR. d, e CCK-8 assays were performed to detect the viability of SPCA1 (d) and A549 (e) with LINC00152 siRNA transfection. f, g Transwell assays were performed to detect the invasion of SPCA1 (f) and A549 (g) with LINC00152 siRNA transfection. *: p < 0.05, **: p < 0.01, ***: p < 0.001