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Fig. 5 | Cancer Cell International

Fig. 5

From: Zebrafish xenograft model of human lung cancer for studying the function of LINC00152 in cell proliferation and invasion

Fig. 5

Knockdown of LINC00152 and block of EGFR have a synergic effect of inhibition in cell proliferation in zebrafish xenograft. a-d Lung cancer cells with NC transfection (a, b) or si-LINC00152 transfection were injected into the PVS of 2-dpf WT zebrafish larvae, and afatinib was bathed in zebrafish culture medium (b, d) or not (a, c). Images were taken by a confocal microscope at 3 dpt. e, f Statistical analysis of the proliferation and invasion with NC or LINC00152 siRNA transfection and afatinib administration or not. ns, not statistically significant, *: p < 0.05. Scale: 100 μm

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