Skip to main content
Fig. 2 | Cancer Cell International

Fig. 2

From: Long non-coding RNA SNHG6 regulates the sensitivity of prostate cancer cells to paclitaxel by sponging miR-186

Fig. 2

Impact of SNHG6 silencing on the proliferation, migration, and invasion of PTX-resistant PCa cells. af PC-3/R and DU145/R cells were transfected with si-SNHG6 or si-NC. a QRT-PCR was performed for the detection of the expression of SNHG6 in PC-3/R and DU145/R cells. b The proliferation ability of PC-3/R and DU145/R cells was assessed using MTT assay. c, d The migration and invasion capacities of PC-3/R and DU145/R cells were determined with transwell assay. e, f The levels of CyclinD1, MMP9, Vimentin, and E-cadherin in PC-3/R and DU145/R cells were detected with western blot analysis. **P < 0.001 and ***P < 0.001

Back to article page