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Fig. 3 | Cancer Cell International

Fig. 3

From: Long non-coding RNA SNHG6 regulates the sensitivity of prostate cancer cells to paclitaxel by sponging miR-186

Fig. 3

Effects of SNHG6 inhibition on the sensitivity of PTX-resistant PCa cells to PTX. ad The si-SNHG6 or si-NC was transfected into PC-3/R and DU145/R cells. a The IC50 value of PC-3/R and DU145/R cells was assessed by MTT assay. b Flow cytometry assay was conducted to assess the apoptosis of PC-3/R and DU145/R cells with PTX (30 nM) treatment. c, d Western blot analysis was employed to measure the protein levels of cleaved casp-3, cleaved casp-9, MRP1, and MDR1 in PC-3/R and DU145/R cells with PTX treatment. *P < 0.05, **P < 0.001 and ***P < 0.001

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