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Fig. 4 | Cancer Cell International

Fig. 4

From: Long non-coding RNA SNHG6 regulates the sensitivity of prostate cancer cells to paclitaxel by sponging miR-186

Fig. 4

SNHG6 targeted miR-186 in PTX-resistant PCa cells. a Bioinformatics database starBase v2.0 was utilized to predict the binding sites between SNHG6 and miR-186. b Dual-luciferase reporter assay was performed to determine the luciferase activities of WT-SNHG6 and MUT-SNHG6 in PC-3/R and DU145/R cells transfected with miR-186 or miR-NC. c RIP was employed to verify the relationship between SNHG6 and miR-186 in PC-3/R and DU145/R cells. d QRT-PCR was applied to assess the expression of miR-186 in PC-3/R and DU145/R cells transfected with si-SNHG6 or si-NC. **P < 0.001 and ***P < 0.001

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Cancer Cell International

ISSN: 1475-2867

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