Skip to main content
Fig. 6 | Cancer Cell International

Fig. 6

From: Long non-coding RNA SNHG6 regulates the sensitivity of prostate cancer cells to paclitaxel by sponging miR-186

Fig. 6

SNHG6 regulated the sensitivity of PTX-resistant PCa cells to PTX by miR-186. a–e The si-NC, si-SNHG6, si-SNHG6 + anti-NC, or si-SNHG6 + anti-miR-186 was transfected into PC-3/R and DU145/R cells. a, b MTT assay was used to analyze the IC50 value of PC-3/R and DU145/R cells. c The apoptotic rate of PC-3/R and DU145/R under PTX (30 nM) treatment was detected through flow cytometry assay. d, e The levels of cleaved casp-3, cleaved casp-9, MRP1, and MDR1 in PC-3/R and DU145/R cells under PTX (30 nM) treatment was evaluated with western blot analysis. *P < 0.05, **P < 0.001 and ***P < 0.001

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us