Fig. 7

Knockdown of SNHG6 elevated the sensitivity of PTX-resistant PCa cells to PTX in vivo. a The curves of tumor volume in the sh-SNHG6 and sh-NC groups with or without PTX treatment. b Mice tumor weight in the sh-SNHG6 and sh-NC groups with or without PTX treatment. c The expression levels of SNHG6 and miR-186 in mice tumor tissues of the sh-SNHG6 and sh-NC groups with or without PTX treatment were analyzed by qRT-PCR. d Western blot analysis of the levels of cleaved casp-3, cleaved casp-9, MRP1, and MDR1 in mice tumor tissues of the sh-SNHG6 and sh-NC groups with or without PTX treatment. *P < 0.05, **P < 0.001 and ***P < 0.001