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Fig. 1 | Cancer Cell International

Fig. 1

From: Significance of tumor mutation burden combined with immune infiltrates in the progression and prognosis of ovarian cancer

Fig. 1

Genome‐wide mutation profiling in OC. A Landscape of mutation profiles in OC samples. Mutation information of each gene in each sample was shown in the waterfall plot, where different colors with specific annotations at the bottom meant the various mutation types. The barplot above the legend exhibited the number of mutation burden. B Cohort summary plot displaying distribution of variants according to variant classification, type and SNV class. Bottom part (from left to right) indicates mutation load for each sample, variant classification type. A stacked barplot shows top ten mutated genes. C Rainfall plot of TCGA ovarian cancer sample TCGA-59-2349-01A-01W-0799-08. Each point is a mutation color coded according to SNV class. D Transition and transversion plot displaying distribution of SNVs in OC classified into six transition and transversion events. Stacked bar plot (bottom) shows distribution of mutation spectra for every sample in the MAF file. E Mutually co-occurring gene pairs in OC displayed as a triangular matrix. F A word cloud generated based on frequency of mutated genes in OC

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