Fig. 2

miR-338-3p could directly interact with circ_0007841 in MM cells. a miR-338-3p was predicted as a candidate target of circ_0007841 by circinteractome software. b, c Dual-luciferase reporter assay was conducted to verify whether miR-338-3p could bind to circ_0007841 in MM cells. d, e RNA-pull down assay was performed to confirm the target relationship between miR-338-3p and circ_0007841 in MM cells. f, g The expression of miR-338-3p was detected in BM-derived plasma cells of MM patients and healthy volunteers, MM cells and nPCs cells by qRT-PCR. h The correlation between the expression of miR-338-3p and circ_0007841 was analyzed using Spearman’s coefficient. i, j The abundance of circ_0007841 and miR-338-3p was examined in H929 and OPM2 cells transfected with Vector or circ_0007841 by qRT-PCR. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001