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Fig. 3 | Cancer Cell International

Fig. 3

From: Synergy between hemagglutinin 2 (HA2) subunit of influenza fusogenic membrane glycoprotein and oncolytic Newcastle disease virus suppressed tumor growth and further enhanced by Immune checkpoint PD-1 blockade

Fig. 3

Lymphocyte proliferation assay. Lymphocyte proliferation was estimated and absorbance was measured at 540 nm. The stimulation index (SI) of splenic cells within different groups was calculated to determine the proliferation activity. The results indicate that NDV-HA2 and NDV groups stimulate significant differences when compared to iNDV-HA2, iNDV, HA, PBS and pcDNA3 control groups. In addition, the stimulation index was significant in iNDV-HA2, iNDV, and HA2 treated groups compared to pcDNA3 and PBS control groups. The results are representative of three independent experiments. ***P < 0.001

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