Skip to main content
Fig. 7 | Cancer Cell International

Fig. 7

From: Synergy between hemagglutinin 2 (HA2) subunit of influenza fusogenic membrane glycoprotein and oncolytic Newcastle disease virus suppressed tumor growth and further enhanced by Immune checkpoint PD-1 blockade

Fig. 7

The expression level of caspase-9 protein in tumor lysate of treated groups was measured using the caspase ELISA kit. Treatment with NDV-HA2 significantly (P < 0.001) increased the level of Caspase-9 compared to control groups (PBS and pcDNA3) and also showed a higher level of caspase-9 (p < 0.01) compared with NDV group. Additionally, all other experimental groups induced a higher level expression of caspase-9 in comparison with control groups (p < 0.001). Data points represent means ± SD of triplicate measurements for three mice. **P < 0.01, ***P < 0.001

Back to article page