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Fig. 8 | Cancer Cell International

Fig. 8

From: Synergy between hemagglutinin 2 (HA2) subunit of influenza fusogenic membrane glycoprotein and oncolytic Newcastle disease virus suppressed tumor growth and further enhanced by Immune checkpoint PD-1 blockade

Fig. 8

Immunohistochemistry of caspase-3 expression in tumor tissue. a Tumor-bearing mice were treated with NDV alone or in combination with HA2 plasmid then sacrificed and tumor tissue was excised to process for IHC studies. Randomly selected areas from each tumor were analyzed. Arrowheads represent immunohistochemical staining of caspase-3 (magnification: ×200). b Comparison between the stained areas of caspase-3 expression using Image J software. Bar graphs indicate the mean percentage (%) of staining area in tumor section of different groups. Values represent the mean ± standard deviation (SD) of three independent experiments. **P < 0.01

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Cancer Cell International

ISSN: 1475-2867

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