Fig. 7From: LncRNA KCNQ1OT1 sponges miR-15a to promote immune evasion and malignant progression of prostate cancer via up-regulating PD-L1A schematic summary of this study. In PC, lncRNA KCNQ1OT1 sponges and negatively regulates miR-15a expression to up-regulate PD-L1. PD-L1, on one hand, activates Ras/ERK signaling and promotes multiple malignant phenotypes of PC cells, and on the other hand inhibits the function of CD8+ T cells, promoting immune evasionBack to article page