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Fig. 6 | Cancer Cell International

Fig. 6

From: Long noncoding RNA LINC00261 suppresses prostate cancer tumorigenesis through upregulation of GATA6-mediated DKK3

Fig. 6

LINC00261 inhibits the growth of prostate cancer cells in vivo. a The growth of tumors in vivo assessed by tumorigenesis in nude mice. b The expression of VEGF and CD31 measured by Immunohistochemistry. c, d The expression of VEGF, CD31, MMP-2 and MMP-9 assessed by Western blot analysis. *p < 0.05 vs. oe-NC group, **p < 0.01 vs. oe-NC group, #p < 0.05 vs. the cells treated oe-LINC00261, ##p < 0.01 vs. the cells treated oe-LINC00261. e The positive correlation between DKK3 and LINC00261 explored by TCGA database. f The poor prognosis of patients with low LINC00261 expression. Statistical data are measurement data and described as mean ± standard deviation. ANOVA was used to compare data among multiple groups followed by Bonferroni post hoc test. The experiment repeated three times

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