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Fig. 1 | Cancer Cell International

Fig. 1

From: Downregulation of long non-coding RNA MAFG-AS1 represses tumorigenesis of colorectal cancer cells through the microRNA-149-3p-dependent inhibition of HOXB8

Fig. 1

High expression of lncRNA MAFG-AS1 and low expression of miR-149-3p are observed in CRC tissues and cells. a The expression of lncRNA MAFG-AS1 in CRC tissues and adjacent tissues (n = 30). b The expression of miR-149-3p in CRC tissues and adjacent tissues (n = 30). c The correlation analysis on the expression of lncRNA MAFG-AS1 and miR-149-3p. d The expression of lncRNA MAFG-AS1 in CRC cell lines (HCT116, LoVo, SW480 and SW1116) and normal colon epithelial cell line NCM460 determined by RT-qPCR. e The expression of miR-149-3p in CRC cell lines (HCT116, LoVo, SW480 and SW1116) and normal colon epithelial cell line NCM460 determined by RT-qPCR. * p < 0.05 vs. the adjacent tissues or NCM460 cell line. Data between two groups were compared by paired t test. The correlation analysis between expression of lncRNA MAFG-AS1 and miR-149-3p was performed using Pearson Correlation Coefficient. Data among multiple groups were compared by one-way ANOVA, followed by Tukey’s post hoc test. The experiment was repeated 3 times independently

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Cancer Cell International

ISSN: 1475-2867

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