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Fig. 2 | Cancer Cell International

Fig. 2

From: Downregulation of long non-coding RNA MAFG-AS1 represses tumorigenesis of colorectal cancer cells through the microRNA-149-3p-dependent inhibition of HOXB8

Fig. 2

Silence of lncRNA MAFG-AS1 or upregulation of miR-149-3p exerts inhibitory effects on proliferation, migration and invasion of CRC cells. a The expression of lncRNA MAFG-AS1 in HCT116 and LoVo cells determined by RT-qPCR. b The expression of miR-149-3p in HCT116 and LoVo cells determined by RT-qPCR. c The HCT116 and LoVo cell proliferation detected by CCK-8 assay. d The HCT116 and LoVo cell migration detected by Transwell assay (scale bar = 50 µm). e The HCT116 and LoVo cell invasion detected by Transwell assay (scale bar = 50 µm). f The HCT116 and LoVo cell apoptosis detected by flow cytometry. Data between two groups were compared by unpaired t test. Data among multiple groups were compared by one-way ANOVA, followed by Tukey’s post hoc test. Data at different time points were analyzed by repeated measures ANOVA, followed by Bonferroni test. The experiment was repeated 3 times independently

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Cancer Cell International

ISSN: 1475-2867

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