CircZFR functions as a sponge of miR-578 to promote breast cancer progression by regulating HIF1A expression

Table 1 Correlation between circZFR expression and the clinicopathological features of BC patients

Characteristics	Number	circZFR expression		P
		High	Low
		35	35
Age (years)				0.473
< 60	33	15	18
≥ 60	37	20	17
Distant metastasis				0.016*
Present	32	11	21
Absent	38	24	14
Tumor size (cm)				0.629
≤ 2	30	16	14
> 2	40	19	21
TNM stage				0.002**
I, II	37	25	12
III, IV	33	10	23
HER-2 status				0.339
Positive	34	15	19
Negative	36	20	16
PR status				0.229
Positive	31	13	18
Negative	39	22	17
ER status				0.473
Positive	37	17	20
Negative	33	18	15

HER-2 human epidermal growth factor receptor-2, PR progesterone receptor, ER estrogen receptor
*P < 0.05, **P < 0.01

ISSN: 1475-2867