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Fig. 6 | Cancer Cell International

Fig. 6

From: Circ_002117 binds to microRNA-370 and promotes endoplasmic reticulum stress-induced apoptosis in gastric cancer

Fig. 6

HERPUD1 is directly targeted by miR-370. a miR-370 binding sites on HERPUD1 predicted by TargetScan. b Target relationship between miR-370 and HERPUD1 determine by dual luciferase assay. c RT-qPCR determining HERPUD1 expression in gastric cancer and adjacent normal tissues (N = 87). d Correlation between miR-370 and HERPUD1 in tissues. e HERPUD1 expression in normal gastric epithelial cells and gastric cancer cell lines determined by RT-qPCR. *p < 0.05 vs. adjacent normal tissues or mimic NC. #p < 0.05 vs. inhibitor NC. Data were shown as the mean ± standard deviation. When two paired group data followed normal distribution and homogeneity of variance, statistical comparison was performed with paired t-test. Two unpaired group which followed normal distribution and homogeneity of variance was analyzed by unpaired t-test. The experiment was repeated in triplicate

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