Fig. 6From: Mitochondrion-mediated iron accumulation promotes carcinogenesis and Warburg effect through reactive oxygen species in osteosarcomaIron-induced AMPK inhibition increased mTORC1 activity. Ferric ammonium citrate (FAC) inhibited expression of phospho-AMPK. Ferric ammonium citrate (FAC) increased phosphor-4EBP1 and phosphor-S6k1 activityBack to article page